Despite her first album failing to make an impact, she continued on with her career and eventually joined a group called Talking Heads where she sang backup for the group during the late 70s and into the early 80s. After releasing a second album that also didn't do so well and becoming tired of touring and changing lables Hendryx decided to take a hiatus from releasing music and touring. She returned to the spotlight when Labelle reunited in 2007. The group released a project titled Back to Now in 2008 and performed together. This reunion sparked Hendryx's passion again and she began to tour and record music again, to wish she also released a jazz & funk album titled It's Time in 2011, to which the album was well received. She had finally started getting the recognition she deserved.
A woman of many talents, she went on to release a children's book titled The Brownies and also a sci-fi musical she co-wrote with writer Charles Randolph titled Skindiver in 2010. She also came out as Bisexual in 2001 interview with The Advocate magazine and became a voice for the LGBTQ community; even going on to join with Cyndi Lauper on her True Colors Tour. She was also very heavily present in raising money to support people living HIV/AIDS. The last album she released was in 2012 titled Mutatis Mutandis.
Fun Fact: Nona Hendryx is a cousin to Jimi Hendrix!